Investigation of scattered dose in a mouse phantom model for pre-clinical dosimetry studies

Tissue-equivalent phantoms are suitable tools for radiation dosimetry investigations. The goal of this study was to determine the scattered dose in a simple phantom model mouse with xenographic tumour using experimental measurements and Monte-Carlo calculations. We manufactured cubic polymethyl methacrylate (PMMA) an extrusion on its side both normal tissue xenograft tumour-bearing mouse. positioned novel add-on collimator, designed by our research group, enable targeted irradiation 20 Gy a137Cs gamma irradiator. EBT3 GAFchromic film utilized measure distribution within phantom. EGSnrc MC code used simulate system calculate comparison measurements. Good agreement observed between simulation results based index analysis. demonstrate that out field (dose tissue) is order 8–9% prescribed when irradiating Our physical useful tool assess tumours.